Glucophage or metformin to lose weight
Atlas, Sanja Percac-Lima. (2017) A First-Trimester Biomarker Panel for Predicting the Development of Gestational Diabetes. Changes in weight and leisure physical activity over time differed significantly among the treatment groups (P. CrossRef 38 Antonio Farina, Elizabeth Eklund, Dalila Bernabini, Mariangela Paladino, Francesca Righetti, Giuseppe Monti, Geralyn Lambert-Messerlian. 20 Diggle PJ, Liang K-Y, Zeger SL. (2016) Inter-relationships between the severity of metabolic syndrome, insulin and adiponectin and their relationship to future type 2 diabetes and cardiovascular disease. Bender, Suzanna Martinez, Christine Kennedy. No deaths were attributed to the study intervention. Endocrinology and Metabolism Clinics of North America 45:4, 819-843. Franz. (2016) Quantification of the type 2 diabetes risk in women with gestational diabetes: a systematic review and meta-analysis of 95,750 women. Reaven, Joshua W. Geiss, Edward W. Kraus. Snehalatha, J. CrossRef 295 Michele Heisler, Elizabeth Kaselitz, Gurpreet K. (2017) Improving access and systems of care for evidence-based childhood obesity treatment: Conference key findings and next steps. Stafford. Pitts, R. (2017) Effects of a culturally adapted lifestyle intervention on cardio-metabolic outcomes: a randomized controlled trial in Iraqi immigrants to Sweden at high risk for Type 2 diabetes. Aronne. Bell, Alain G. CrossRef 160 Y. The incidence of diabetes was 39 percent lower (95 percent confidence interval, 24 to 51 percent) in the lifestyle-intervention group than in the metformin group. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Journal of Diabetes and its Complications 30:7, 1333-1338. Sosenko, Dan Ziegler. Validity and reproducibility of a food frequency interview in a multi-cultural epidemiology study. (2016) Standards of care for type 2 diabetes in China. Discovery and Development of Antidiabetic Agents from Natural Products, 209-228. 8 years. Kimokoti, Barbara E. 2016. M. Diabetes Mellitus in Developing Countries and Underserved Communities, 49-61. Gray, Thomas Yates, Jacqui Troughton, Kamlesh Khunti, Melanie J. Kirkland. L. Tepolt, Andrea Stracciolini, Mininder S. (2016) A Prospective Programmatic Cost Analysis of Fuel Your Life. White, Jose M. Ozanne, Hassan Rahmoune, Paul C. CrossRef 198 D. The values rose in parallel in all three groups in subsequent years. (2016) Impact of lifestyle intervention in primary prevention of Type 2 diabetes did not differ by baseline age and BMI among Asian-Indian people with impaired glucose tolerance. Matney, S. The diagnosis is often delayed until complications are present. The incidence of diabetes was reduced by 58 percent with the lifestyle intervention and by 31 percent with metformin, as compared with placebo. Kernan. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Hayward. 2017. Castro Sweet, Vinay Chiguluri, Rajiv Gumpina, Paul Abbott, Erica N. (2016) Physical Activity, Diet Quality, and Mortality among Community-Dwelling Prefrail and Frail Older Adults. Eckel, Leif Groop, Per-Henrik Groop, Yehuda Handelsman, Richard A. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Ali, K. (2016) Preventing Diabetes: Early Versus Late Preventive Interventions: Table 1. Psaty. Nathan, David M. CrossRef 191 Sang Ouk Chin, Changwon Keum, Junghoon Woo, Jehwan Park, Hyung Jin Choi, Jeong-taek Woo, Sang Youl Rhee. (2016) Exercise-stimulated glucose uptake — regulation and implications for glycaemic control. Heymsfield, Steven B. Baldo, S. (2016) Motivational, volitional and multiple goal predictors of walking in people with type 2 diabetes. Herman. (2017) The Lifestyle Intervention for the Treatment of Diabetes study (LIFT Diabetes): Design and baseline characteristics for a randomized translational trial to improve control of cardiovascular disease risk factors. CrossRef 117 Ronald C. Cho, Chang Ho Ahn, Joon Ho Moon, Soo Heon Kwak, Sung Hee Choi, Soo Lim, Kyong Soo Park, Boyd E. Abbott, Manohar L. All tests were performed without interrupting the assigned treatment, except that placebo or metformin was not taken on the morning of the test. Rothberg. Ledbury, M. (2016) Effects of a Community-Based Healthy Lifestyle Intervention Program (Co-HELP) among Adults with Prediabetes in a Developing Country: A Quasi-Experimental Study. Jensen. AGE. 2017. (2016) Advancing a Comprehensive Approach to the Study of Lower Urinary Tract Symptoms. Hanson, Shane A. (2016) Predictive value of serum testosterone for type 2 diabetes risk assessment in men. 2017. J. S. CrossRef 51 C. Wadden, Thomas A. CrossRef 157 Kimberly Gudzune. Goebel-Fabbri, M. (2016) Testosterone and depressive symptoms among men in the Diabetes Prevention Program. The incidence of diabetes was 11. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. (2017) Accessible weight loss: Adapting a lifestyle intervention for adults with impaired mobility. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 71:11, 1415-1423. Agharanya, N. Garofolo, G. CrossRef 41 Minjun Wang, Hong Xin, Wenbo Tang, Yiming Li, Zhaoyun Zhang, Linling Fan, Lei Miao, Bo Tan, Xiling Wang, Yi Zhun Zhu. R. Anton, Ara Jo, Maya C. Wells, Theodore J. (2016) Exercise and diet in the management of nonalcoholic fatty liver disease. The Diabetes Prevention Program: recruitment methods and results. (2017) Dynamics of Diabetes and Obesity: Epidemiological Perspective. Diabetes Mellitus in Developing Countries and Underserved Communities, 1-5. Lemon, M. (2016) Use of Mobile Health Technology in the Prevention and Management of Diabetes Mellitus. Janney, Hyungjin Myra Kim, Shira Maguen, Katherine D. These effects were similar in men and women and in all racial and ethnic groups. The study was designed to answer the following primary questions: Does a lifestyle intervention or treatment with metformin, a biguanide antihyperglycemic agent, prevent or delay the onset of diabetes. T. Adobe Flash Player is required to view this feature. Ford, J. W. Kangas, P. Insulin secretagogues for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus. (2017) Physical Activity and Abnormal Blood Glucose Among Healthy Weight Adults. No periods for 2 mnths pregnancy kit -ve. (2016) Whole food approach for type 2 diabetes prevention. King, E. Krentz. (2016) Comparative evaluation of clinical and inflammatory factors in response to the pharmacological managements in metabolic syndrome. (2016) Social Disorder in Adults with Type 2 Diabetes: Building on Race, Place, and Poverty. CrossRef 302 Megan Erickson, Katie Braun, Riesa List, Anne Utech, Carolyn Moore, Donna L. (2016) Self-determination theory and weight loss in a Diabetes Prevention Program translation trial. CrossRef 376 Shoaib Mohammad, Jamal Ahmad. Haughton, D. 9) for metformin. Each data point represents the mean value for all participants examined at that time. The initiation of treatment with half a tablet was optional. (2016) The role of patient education in the prevention and management of type 2 diabetes: an overview. Schlichtman, Monica E. Garcia. CrossRef 233 Anne Raben. CrossRef 335 Kavita Singh, Harish Ranjani, Elizabeth Rhodes, Mary Beth Weber. Winett. Diabetes Mellitus in Developing Countries and Underserved Communities, 7-31. Rinaldo, E. (2016) Seasonal weight variation patterns in seven countries located in northern and southern hemispheres. Vasquez, Ramin Naderi, Nicole Jeffery, Haley Hedlin, FeiFei Qin, Teresa LaFromboise, Nancy Megginson, Craig Pasqua, Orena Flores, Rhonda McClinton-Brown, Jill Evans, Randall S. Giles, D. Pearson, Ashfaq Ali, Paul W. Montella. (2016) The importance and strategy of diabetes prevention. The analysis included all participants, whether or not diabetes had been diagnosed. (2016) Associations between non-traditional lipid measures and risk for type 2 diabetes mellitus in a Chinese community population: a cross-sectional study. (2016) Effectiveness of community-based exercise intervention programme in obese adults with metabolic syndrome. Shen, R. (2016) Understanding How Overweight and Obese Emerging Adults Make Lifestyle Choices. Risk reduction, heterogeneity among strata, and interactions between treatment assignments and covariates were assessed by proportional-hazards regression. CrossRef 13 Rachele Pojednic, Elizabeth Frates. Want to know what people are talking about right now. P. (2016) Impact of a community-based lifestyle intervention program on health-related quality of life. (2016) Plasma lipid levels predict dysglycemia in a biracial cohort of nondiabetic subjects: Potential mechanisms. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Adobe Flash Player is required to view this feature. Y. Bynum. Adobe Flash Player is required to view this feature. Pomposelli, M. Journal of Occupational and Environmental Hygiene 13:6, 451-463. Lobstein, S. 9 (95 percent confidence interval, 5. Ganda, A. CrossRef 100 Layla Parast, Tianxi Cai, Lu Tian. New York: Oxford University Press, 1994. Sniehotta, Louise McCombie, Naomi Brosnahan, Hazel Ross, John C. 2017. CrossRef 122 Anne Neumann, Lars Lindholm, Margareta Norberg, Olaf Schoffer, Stefanie J. (2017) Treatment options to prevent diabetes in subjects with prediabetes: efficacy, cost effectiveness and future outlook. Hodish. Research in Special Populations. (2016) Immigration and dietary patterns in South Asian Canadians at risk for diabetes. Most contain a combination of estrogen and a progestin. Braginsky, M. Lui, V. Glycemic Changes In the first year, there was a similar reduction in the mean fasting plasma glucose values in the metformin and lifestyle-intervention groups, whereas the values rose in the placebo group ( Figure 3 Figure 3 Fasting Plasma Glucose Concentrations (Panel A) and Glycosylated Hemoglobin Values (Panel B) According to Study Group. CrossRef 112 Akira Mitsuhashi, Takashi Uehara, Shinsuke Hanawa, Makio Shozu. CrossRef 370 Frank L. Smith, C. A. Chen, P. CrossRef 196 Scott Kahan, Robert F. CrossRef 355 Uma Mudaliar, Azadeh Zabetian, Michael Goodman, Justin B. Libby III, R. M. Significant heterogeneity indicates that treatment effects differed according to the values of the covariates. Chapter 3 Health Aspects of Mono- and Disaccharides. CrossRef 247 Yosefa Bar-Dayan, Mona Boaz, Zohar Landau, Feldbrin Zeev, Daniela Jakubowicz, Julio Wainstein. Harhay. Primary Prevention of Type 2 Diabetes: An Imperative for Developing Countries. Chen, Robert C. Dinh, M. (2016) What we have learned about treating mild gestational diabetes mellitus. Dollahite, Cindy Fitch, Jan Carroll. (2017) Therapeutic approaches targeting inflammation for diabetes and associated cardiovascular risk. Bray, Fernand Labrie, Sherita Hill Golden. Jacobsen, L. 6 kg in the placebo, metformin, and lifestyle-intervention groups, respectively (P Incidence of Diabetes The cumulative incidence of diabetes was lower in the metformin and lifestyle-intervention groups than in the placebo group throughout the follow-up period ( Figure 2 Figure 2 Cumulative Incidence of Diabetes According to Study Group. Mueser, Stephen J. Adobe Flash Player is required to view this feature. CrossRef 69 Faiza Siddiqui, Azra Kurbasic, Ulf Lindblad, Peter M. Urologic Oncology: Seminars and Original Investigations 35:1, 21-29. Koehlmoos, Louis W. Moore. F. Goldfine, Steven E. S. 9 percent, 21. (2016) Physical Activity Prescription. Mau, K. CrossRef 64 S. Reynolds, Ashley Duncan, Devonia Kruimer, Bernard J. S. Ciliberto, D. When you come to WebMD Answers with questions, you also bring answers. Lowe, M. CrossRef 337 Luc Van Gaal, Eveline Dirinck. Oldenburg, R. The reduction in the average fasting plasma glucose concentration was similar in the lifestyle-intervention and metformin groups, but the lifestyle intervention had a greater effect than metformin on glycosylated hemoglobin, and a larger proportion of participants in the lifestyle-intervention group had normal post-load glucose values at follow-up. Metzger, Hak C. (2017) Prediabetes in Obese Adolescents. Endoluminal Procedures. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Conclusions Lifestyle changes and treatment with metformin both reduced the incidence of diabetes in persons at high risk. (2016) Occupational physical activity assessment for chronic disease prevention and management: A review of methods for both occupational health practitioners and researchers. (2017) Physical inactivity: a risk factor and target for intervention in renal care. Stone. Important: The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, blogs, or WebMD Answers are solely those of the User, who may or may not have medical or scientific training. Williams. Mohlke, L. (2016) Dietary Interventions for Type 2 Diabetes: How Millet Comes to Help. Frisard, S. P. (2017) Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis. Doctor suggested meprate for 5 days no periods feel weak, nausea, tired, vomit. Journal of Nutrition Education and Behavior 48:10, 743-748. Hill, Heather Daly, Lorraine Martin Stacey, Margaret A. Jaime Miranda. (2016) Impact of a behavioral weight loss intervention on comorbidities in overweight and obese breast cancer survivors. ). : National Heart, Lung, and Blood Institute Information Center, 1987. CrossRef 27 Elena Dingle, Preneet Cheema Brar. (2016) Risk assessment and management of post-transplant diabetes mellitus. (2016) Evaluation of a community-based behavioral weight loss program in Chinese adults: A randomized controlled trial. Fitzgibbon, M. (2016) Psychosocial mediators of a theory-based resistance training maintenance intervention for prediabetic adults. Shoelson. CrossRef 239 Lykke Sylow, Maximilian Kleinert, Erik A. (2016) Prediabetes. Bethesda, Md. M. The lifestyle intervention was highly effective in all subgroups. CrossRef 336 Jaakko Tuomilehto, Peter E. Current Physical Medicine and Rehabilitation Reports 4:3, 223-232. Matsui. (2016) Designing a Culturally Appropriate Visually Enhanced Low-Text Mobile Health App Promoting Physical Activity for Latinos. Adobe Flash Player is required to view this feature. Washington, D. (2016) Cancer Prevention: Lessons Learned and Future Directions. Storti, Dana Dabelea, Sharon Edelstein, Hermes Florez, Paul W. (2016) Emotional eating is associated with weight loss success among adults enrolled in a weight loss program. Hagerty, R. Goodman, Sarah Olender. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). (2016) Using a public health station for screening of undiagnosed dysglycemia and hypertension. Herman. CrossRef 274 Amy Rothberg, Michael Lanham, John Randolph, Christine Fowler, Nicole Miller, Yolanda Smith. Young, A. Edelman, R. Talukder, Muhammad Ashique Haider Chowdhury, Ali Tanweer Siddiquee, Shyfuddin Ahmed, Sonia Pervin, Sushmita Khan, Khaled Hasan, Tracey L. CrossRef 179 Bing-Yin Shi. CrossRef 131 Jutta K. Amore, M. (2016) The 10-year trend of adult diabetes, prediabetes and associated risk factors in Tehran: Phases 1 and 4 of Tehran Lipid and Glucose Study. CrossRef 39 Longo, Dan L. (2017) Effectiveness and cost-effectiveness of interventions that cause weight loss and reduce the risk of cardiovascular disease. (2016) Predictors of health-promoting behaviors in patients with coronary artery disease in the Iranian population. (2016) Hypertriglyceridemia: A simple approach to identify insulin resistance and enhanced cardio-metabolic risk in patients with prediabetes. The standard lifestyle recommendations for the medication groups were provided in the form of written information and in an annual 20-to-30-minute individual session that emphasized the importance of a healthy lifestyle. R. Pagoto. Cook, M. Chen, T. CrossRef 383 Tim Harries, Ruth Rettie. CrossRef 120 Chunling Wang, Zhizhong Dong, Zhe Yi, Jian Ying, Geng Zhang. Umpierrez. (2016) A Systematic Review of Biomarkers and Risk of Incident Type 2 Diabetes: An Overview of Epidemiological, Prediction and Aetiological Research Literature. S. (2016) Prevalence of undiagnosed hyperglycaemia in patients presenting to the Department of Emergency Medicine with no known history of diabetes. (2016) Reported Health Behaviour Changes after a Diagnosis of Gestational Diabetes Mellitus among Ethnic Minority Women Living in Canada. Aronoff, M. (2016) The utility of weight loss medications after bariatric surgery for weight regain or inadequate weight loss: A multi-center study. Marquez, Elizabeth Spurrell-Huss, Nicole Hollingsworth, Amanda S. Libra, G. (2016) Leveraging Genetics to Advance Type 2 Diabetes Prevention. Korean Journal of Health Education and Promotion 33:4, 79-87. Adobe Flash Player is required to view this feature. 2016. CrossRef 256 Fatemeh Hajizadeh-Sharafabad, Mohammad Alizadeh. Zibellini, R. Niessen. (2016) A pilot randomized trial of technology-assisted goal setting to improve physical activity among primary care patients with prediabetes. Journal of the American Academy of Orthopaedic Surgeons 24:12, 865-871. Wilding, Robert E. Adobe Flash Player is required to view this feature. Lewis, Dorry L. Kral, Rita R. Inouye, M. This means that a cookie will stay on your computer even when you exit or close your browser which may reduce your levels of privacy and security. D. A 16-lesson curriculum covering diet, exercise, and behavior modification was designed to help the participants achieve these goals. (2017) Intensive Patient Education Improves Glycaemic Control in Diabetes Compared to Conventional Education: A Randomised Controlled Trial in a Nigerian Tertiary Care Hospital. 2017. (2016) Successful weight reduction and maintenance by using a smartphone application in those with overweight and obesity. Sauver. M. Sherry Chow. C. CrossRef 148 Junmei Yin, Alice P. The incidence of diabetes in our placebo group (11. (2017) Diabetes Prevention Program Translation in the Veterans Health Administration. Driver, Neil J. 252. Multiplex Biomarker Approaches in Type 2 Diabetes Mellitus Research. (2016) Evidence-based practice use of quick-release bromocriptine across the natural history of type 2 diabetes mellitus. Venkat Narayan. Dunn, Barnett S. Boulton, Eva L. Kashyap. (2017) Perinatal outcomes after adopting 1- versus 2-step approach to diagnosing gestational diabetes. (2016) One-hour post-load plasma glucose level during the OGTT predicts dysglycemia. H. (2016) Cardiac conditioning for healthy individuals: primary prevention of heart disease. Duke, Timothy M. Sinkule-Kam, J. Mohideen, S. (2016) Feasibility of Behavioral Weight Loss Treatment Enhanced with Peer Support and Mobile Health Technology for Individuals with Serious Mental Illness. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. (2016) A complex behavioural change intervention to reduce the risk of diabetes and prediabetes in the pre-conception period in Malaysia: study protocol for a randomised controlled trial. (2016) Weight Loss Interventions in Older Adults with Obesity: A Systematic Review of Randomized Controlled Trials Since 2005. The diagnosis of diabetes was based on the criteria of the American Diabetes Association. (2016) One-hour post-load hyperglycemia combined with HbA1c identifies pre-diabetic individuals with a higher cardio-metabolic risk burden. (2016) Process evaluation of a randomised controlled trial of a diabetes prevention intervention in Dutch primary health care: the SLIMMER study. Willett, Qi Sun, Frank B. Dias, N. CrossRef 109 Long Zhou, Huanhuan Liu, Xiaoxiao Wen, Yaguang Peng, Yu Tian, Liancheng Zhao. J. (2017) A Clinical Practice Lifestyle Intervention for Type 2 Diabetes. (2016) Dietary and Behavioral Approaches in the Management of Obesity. CrossRef 21 Kelly A Wagner, Ethan Braun, Seth M Armah, Diarmuid Horan, Lisa G Smith, Julie Pike, Wanzhu Tu, Marc T. Kumar, G. CrossRef 52 Giovanni Domenico De Palma, Alfredo Genco, Massimiliano Cipriano, Gaetano Luglio, Roberta Ienca. (2017) AMPK Serves as a Therapeutic Target Against Anemia of Inflammation. CrossRef 10 Smithamol Sithara, Tamsyn M Crowley, Ken Walder, Kathryn Aston-Mourney. Whether the results would be similar in persons with an isolated elevation of the fasting or post-load glucose concentration or other risk factors for diabetes is likely but unknown. Richardson. CrossRef 195 Ellen JI van Dongen, Geerke Duijzer, Sophia C Jansen, Josien ter Beek, Johanna M Huijg, Joanne N Leerlooijer, Gerrit J Hiddink, Edith JM Feskens, Annemien Haveman-Nies. (2017) Effectiveness of a Group-Based Culturally Tailored Lifestyle Intervention Program on Changes in Risk Factors for Type 2 Diabetes among Asian Indians in the United States. Floyd, Bruce M. 2017. CrossRef 86 William H. (2017) Growth Differentiation Factor 15 as a Novel Biomarker for Metformin. Kelly, Thomas H. C. 1, 2. (2016) Perception of Risk for Developing Diabetes Among Foreign-Born Spanish-Speaking US Latinos. Figure 4 Figure 4 Participants with Normal Plasma Glucose Values, According to Study Group. CrossRef 66 Tao Zheng, Wei Xie, Liling Xu, Xiaoying He, Ya Zhang, Mingrong You, Gong Yang, You Chen. (2016) The Effectiveness of Different Diet Strategies to Reduce Type 2 Diabetes Risk in Youth. Landon. Blaak. CrossRef 119 Norliza Ibrahim, Foong Ming Moy, Intan Attikah Nur Awalludin, Zainudin Mohd Ali, Ikram Shah Ismail, Gianpaolo Reboldi. M. Vasan. Stone, Naina Patel, Kamlesh Khunti, Thomas Yates, Laura J. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 71:11, 1424-1434. CrossRef 277 Eun Ju Lee, Tae Nyun Kim. Davies. CrossRef 93 Miki Sato, Hirokazu Ito, Hiroko Sugimoto, Tetsuya Tanioka, Yuko Yasuhara, Rozzano Locsin, Beth King. Reidy, J. Harhay, Meera N. H. Vandenberg. McPherson, M. Wilson, Sherry L. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Gregg, Robert S. adults: the Third National Health and Nutrition Examination Survey, 1988-1994. Zhang, H. Braxter, Bonnie Mowinski Jennings. Selvam, L. (2016) The Impact of a Worksite-Based Diabetes Prevention Intervention: A Pilot Study. V. Katiyar, Kauser Usman, Sanjay Khattri. Misra-Hebert, Bo Hu, Glen Taksler, Robert Zimmerman, Michael B. Florez. Adobe Flash Player is required to view this feature. Hospitalization and mortality rates were unrelated to treatment. Malin, Sangeeta R. (2016) Comment on Koivusalo et al. The lifestyle intervention was more effective than metformin. CrossRef 37 Jaume Padilla, Pamela K Thorne, Jeffrey S Martin, R Scott Rector, Sadia Akter, J Wade Davis, M Harold Laughlin, Nathan T Jenkins. Tokunaga, R. Tomolo, Usha Ramakrishnan, K. Pearson, Naveed Sattar,. CrossRef 380 Jianping Weng, Linong Ji, Weiping Jia, Juming Lu, Zhiguang Zhou, Dajin Zou, Dalong Zhu, Liming Chen, Li Chen, Lixin Guo, Xiaohui Guo, Qiuhe Ji, Qifu Li, Xiaoying Li, Jing Liu, Xingwu Ran, Zhongyan Shan, Lixin Shi, Guangyao Song, Liyong Yang, Yuzhi Yang, Wenying Yang,. CrossRef 138 Mary-Anne Doyle, Joel Singer, Terry Lee, Miriam Muir, Curtis Cooper. (2016) Changes in ideal cardiovascular health status and risk of new-onset type 2 diabetes. M. (2016) Effect of diet-induced weight loss on muscle strength in adults with overweight or obesity - a systematic review and meta-analysis of clinical trials. (2016) Fresh Start, a postpartum weight loss intervention for diverse low-income women: design and methods for a randomized clinical trial. Nelson, G. Scherer. 2016. At one month, the dose of metformin was increased to 850 mg twice daily, unless gastrointestinal symptoms warranted a longer titration period. H. Marrero, Chandan Saha, Ronald T. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Clark, Kimberly A. 0 MG ON WEIGHT AND RISK FACTORS IN HISPANIC VERSUS NON-HIPANIC POPULATIONS: SUBGROUP ANALYSIS FROM SCALE RANDOMIZED TRIALS. CrossRef 299 Yosefa Bar-Dayan, Irena Zilberman, Mona Boaz, Zohar Landau, Mariela Glandt, Daniela Jakubowicz, Julio Wainstein. Estabrook, C. 4 to 9. CrossRef 263 Michael Bergman, Angela Chetrit, Jesse Roth, Ram Jagannathan, Mary Sevick, Rachel Dankner. Adobe Flash Player is required to view this feature. Methods We conducted a clinical trial involving persons at 27 centers who were at high risk for diabetes. MMWR. Luetke. CrossRef 34 Thunyarat Anothaisintawee, Dumrongrat Lertrattananon, Sangsulee Thamakaison, Kristen L. (2016) Impact of low-carbohydrate diet on renal function: a meta-analysis of over 1000 individuals from nine randomised controlled trials. (2016) Establishing an Effective Primary Care Provider Referral Network for the National Diabetes Prevention Program. CrossRef 288 Naji Alamuddin, Thomas A. Adobe Flash Player is required to view this feature. Schwarz. (2016) The healthy living partnerships to prevent diabetes and the diabetes prevention program: a comparison of year 1 and 2 intervention results. Browning. (2017) Characterisation of fatty acid metabolism in different insulin-resistant phenotypes by means of stable isotopes. Media in This Article Figure 3 Fasting Plasma Glucose Concentrations (Panel A) and Glycosylated Hemoglobin Values (Panel B) According to Study Group. Quick links to the most popular questions and answers. Endocrinology and Metabolism Clinics of North America 45:4, 967-1009. Cheng, Kim Connelly, David Fitchett, Ronald Goldenberg, Shaun G. Seimon, C. CrossRef 258 Sundararajan Srikanth, Prakash Deedwania. CrossRef 4 Chaiyavat Chaiyasut, Bhagavathi Sivamaruthi, Noppawat Pengkumsri, Waranya Keapai, Periyanaina Kesika, Manee Saelee, Parichart Tojing, Sasithorn Sirilun, Khontaros Chaiyasut, Sartjin Peerajan, Narissara Lailerd. The investigators and the participants were unaware of the results of these measurements and were informed only if the results exceeded the specified threshold for a change in the treatment. Jang. CrossRef 222 Ibiye Owei, Nkiru Umekwe, Jim Wan, Samuel Dagogo-Jack. Joseph, Sherita Hill Golden. Patel, Ranjita Misra, Sudha Raj, Ashok Balasubramanyam. In summary, our study showed that treatment with metformin and modification of lifestyle were two highly effective means of delaying or preventing type 2 diabetes. (2016) Reconciliation of Type 2 Diabetes Remission Rates in Studies of Roux-en-Y Gastric Bypass. Trischitta. CrossRef 205 Parham Parto, Carl J Lavie, Ross Arena, Samantha Bond, Dejana Popovic, Hector O Ventura. 4 percent in the placebo, metformin, and lifestyle-intervention groups, respectively. CrossRef 165 Renu Vyas, Sanket Bapat, Esha Jain, Muthukumarasamy Karthikeyan, Sanjeev Tambe, Bhaskar D. Any of the OTC medications that people take for headache and fever will help for someone that has hypertension, just be sure and read the label. (2016) Development of a lifestyle intervention using the MRC framework for diabetes prevention in people with impaired glucose regulation. Caenepeel-Mills, S. Ray, Enza Gucciardi, Julia Lowe, Denice Feig, Geetha Mukerji, Wei Wu, Lorraine L. Commisso, C. T. (2016) Maximizing retention in long-term clinical trials of a weight loss agent: use of a dietitian support team. CrossRef 372 Zhengxiong Yang, Zhiping Yu, Yingying Jiang, Yamin Bai, Karen Miller-Kovach, Wenhua Zhao, Gary D. , Suite 750, Rockville, MD 20852. Heard, C. CrossRef 307 Shu-Hung Chang, Miao-Chuan Chen, Nai-Hui Chien, Hsih-Fong Lin. F. CrossRef 110 Costas Thomopoulos, Georgios Katsimagklis, Thomas Makris. CrossRef 308 Niroomand Mahtab, Hadaegh Farzad, Bahaeddini Mohsen, Darvishi Nakisa. Harris, S. E. Stoecker. 2017. Pan, C. Journal of Photochemistry and Photobiology B: Biology 166, 86-93. (2016) Sustained influence of metformin therapy on circulating glucagon-like peptide-1 levels in individuals with and without type 2 diabetes. Betts, Katherine Froehlich-Grobe. (2016) Pharmacological Management of Obesity in Patients with Type 2 Diabetes: An Update. Mann, Sheila Williams, Bernard J. Participants were encouraged to follow the Food Guide Pyramid 14 and the equivalent of a National Cholesterol Education Program Step 1 diet, 15 to reduce their weight, and to increase their physical activity. (2016) Lifestyle changes and cardiovascular risk reduction in diabetes. L. 2016. 2016. Mouton. Lin. (2017) Relationship between Lifestyle, Quality of Sleep, and Daytime Drowsiness of Nursing Students of University A. Goff. CrossRef 172 Thunyarat Anothaisintawee, Sirimon Reutrakul, Eve Van Cauter, Ammarin Thakkinstian. The number of participants decreased over time because of the variable length of time that persons were in the study. (2016) Consumption of citrus and cruciferous vegetables with incident type 2 diabetes mellitus based on a meta-analysis of prospective study. Adobe Flash Player is required to view this feature. Holman, A. Diabetes mellitus, coronary heart disease incidence, and death from all causes in African American and European American women: the NHANES I epidemiologic follow-up study. Henry, M. Star, Griffin P. Adobe Flash Player is required to view this feature. Ryff. (2017) Peripheral insulin resistance rather than beta cell dysfunction accounts for geographical differences in impaired fasting blood glucose among sub-Saharan African individuals: findings from the RODAM study. (2016) Management of Dyslipidemia in Patients with Hypertension, Diabetes, and Metabolic Syndrome. Ganley. (2016) Use of a web-based educational intervention to improve knowledge of healthy diet and lifestyle in women with Gestational Diabetes Mellitus compared to standard clinic-based education. Methods We randomly assigned 3234 nondiabetic persons with elevated fasting and post-load plasma glucose concentrations to placebo, metformin (850 mg twice daily), or a lifestyle-modification program with the goals of at least a 7 percent weight loss and at least 150 minutes of physical activity per week. Di Bonito, G. Relation of impaired fasting and postload glucose with incident type 2 diabetes in a Dutch population: the Hoorn Study. Cheah, Roslinah Ali, Ramli Zainal, Tahir Aris, Zainudin Mohd Ali, Priya Matzen, Regien Biesma, Jens Aagaard-Hansen, Mark A. Adobe Flash Player is required to view this feature. Many people want insurance but feel that deductibles and co-pays make it too costly to actually go to the doctor. Lagisetty, Shubadra Priyadarshini, Stephanie Terrell, Mary Hamati, Jessica Landgraf, Vineet Chopra, Michele Heisler. By then, we had obtained evidence of efficacy on the basis of 65 percent of the planned person-years of observation. Sajitha, F. Metformin was less effective in persons with a lower base-line body-mass index or a lower fasting plasma glucose concentration than in those with higher values for these variables. Does their effectiveness differ according to age, sex, or race or ethnic group. G. Adobe Flash Player is required to view this feature. Adverse Events The rate of gastrointestinal symptoms was highest in the metformin group, and the rate of musculoskeletal symptoms was highest in the lifestyle-intervention group ( Table 3 Table 3 Adverse Events. CrossRef 305 L. (2016) Diabetes Prevention Interventions in Latin American Countries: a Scoping Review. Franks. (2016) The Application of Genomics in Diabetes: Barriers to Discovery and Implementation. U. (2016) Financial Incentives and Diabetes Disease Control in Employees: A Retrospective Cohort Analysis. (2016) Association between anorexia nervosa and type 2 diabetes in Sweden: Etiological clue for the primary prevention of type 2 diabetes. Riccardi, A. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. (2016) Pharmacological Approaches in the Treatment and Maintenance of Weight Loss. (2017) The Effect of Individual and Neighbourhood Socioeconomic Status on Diabetes Mellitus Survival in Working Age Patients in Taiwan. Venn. (2017) Comparative prognostic performance of definitions of prediabetes: a prospective cohort analysis of the Atherosclerosis Risk in Communities (ARIC) study. CrossRef 321 Hua Sui, Nijing Sun, Libin Zhan, Xiaoguang Lu, Tuo Chen, Xinyong Mao, Klaus Ebmeier. Shaw, Michael Horowitz, Adam M. Farshchi. Miller, Andrea M. Hitman, Shakila Thangaratinam. (2017) Metformin and blood pressure lowering. Havranek. Venkat Narayan. Orlando. (2017) Outcomes of a Digital Health Program With Human Coaching for Diabetes Risk Reduction in a Medicare Population. (2016) Cost Savings From Utilization of an Ambulatory Surgery Center for Orthopaedic Day Surgery. Pasquel, Guillermo E. Vandenberg, Phaedra Corso, Heather Padilla, Heather Zuercher. J. Its effect was significantly greater among persons with lower base-line glucose concentrations two hours after a glucose load than among those with higher base-line glucose values. 2017. Nathan. Gibson, M. CrossRef 271 Hyekyeong Kim. CrossRef 150 Sidra Azim, Sangeeta R. Adobe Flash Player is required to view this feature. Inge. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Panel A shows the proportions of participants with normal glucose values in the fasting state ( shows the percentage of participants who had normal glucose concentrations (fasting values, post-load values, and both) at each annual examination. Svetkey. Fukuhara, J. However, if your employer tells you it is eliminating insurance because of the law, I would be wary of the. The average weight loss was 0. Parkes, M. Ariel, Michael G. Fabreau, Sridharan Raghavan, Katherine Kentoffio, Yuchiao Chang, Wei He, Steven J. Lu, Y. Sills, Linda A. (2016) Improving treatment and liver fibrosis outcomes with metformin in HCV-HIV co-infected and HCV mono-infected patients with insulin resistance: study protocol for a randomized controlled trial. Foo, S. Ginsburg, Lori A. (2017) Effects of Acarbose on the Gut Microbiota of Prediabetic Patients: A Randomized, Double-blind, Controlled Crossover Trial. S. Journal of Nutrition in Gerontology and Geriatrics 35:4, 253-266. Subsequent individual sessions (usually monthly) and group sessions with the case managers were designed to reinforce the behavioral changes. The Diabetes Prevention Program: baseline characteristics of the randomized cohort. CrossRef 358 Mohammed K. Egerman. Journal of Immigrant and Minority Health 18:6, 1334-1342. Ali. CrossRef 326 Xiujuan Jia, Lina Zhong, Yan Song, Yi Hu, Guimei Wang, Shuqin Sun. Endocrinology. I had achilles tendinitis when I was younger and I would feel the pain whenever I. CrossRef 387 Terri Huynh, Neda Ghaffari, Jamie Bastek, Celeste Durnwald. The Global Burden of Diabetes. Behrends, M. CrossRef 79 Ella Zomer, Rachel Leach, Christine Trimmer, Tim Lobstein, Stephen Morris, William P. Prospective Cohorts. Adobe Flash Player is required to view this feature. Nicosia, C. Even if you select this option there are some features of our site that still require you to log in for privacy reasons. Adobe Flash Player is required to view this feature. Gutierrez, Linda C. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. M. CrossRef 221 M. M. Simonson, F. (2016) Evaluation of US Veterans Nutrition Education for Diabetes Prevention. D. (2016) Uptake of the centers for medicare and medicaid obesity benefit: 2012-2013. De Laurentiis, M. 2016. Campbell, Amanda Alberga, Laura C. Halter, Nir Barzilai. Malloy, C. Yadav. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Wareham, Christian Herder. CrossRef 298 M D DeBoer, M J Gurka, J A Morrison, J G Woo. Bailey, Andrew J. CrossRef 343 Xiaoxue Liu, Jihong Shi, Anxin Wang, Qiaofeng Song, Zhe Huang, Chenrui Zhu, Xin Du, Ying Zhang, Shuohua Chen, Xizhu Wang, Shouling Wu. CrossRef 340 Madeline Murguia Rice, Mark B. Bartels. (2016) Activity and Sedentary Time 10 Years After a Successful Lifestyle Intervention: The Diabetes Prevention Program. (2016) Association between Work-Related Stress and Risk for Type 2 Diabetes: A Systematic Review and Meta-Analysis of Prospective Cohort Studies. The study, however, was not designed to test the relative contributions of dietary changes, increased physical activity, and weight loss to the reduction in the risk of diabetes, and the effects of these components remain to be determined. Knutson, Ammarin Thakkinstian, Sirimon Reutrakul. Riggs, S. (2016) EFFECTS OF LIRAGLUTIDE 3. Gestational Diabetes Mellitus Can Be Prevented by Lifestyle Intervention: The Finnish Gestational Diabetes Prevention Study (RADIEL): A Randomized Controlled Trial. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Ram, S. Waters, Gerald Reaven. 9 (95 percent confidence interval, 8. Changes in fasting glucose values over time in the three groups differed significantly (P Figure 2 Cumulative Incidence of Diabetes According to Study Group. Adobe Flash Player is required to view this feature. Minges, Caroline R. Venkat Narayan, Viswanathan Mohan. Tsai, Edward P. Khan, D. Egede. Participants assigned to the lifestyle intervention had much greater weight loss and a greater increase in leisure physical activity than did participants assigned to receive metformin or placebo. Dupont, L. Segev. (2016) Eulogy for the clinical research center. (2016) Multiple Risk Factor Interventions for Primary Prevention of Cardiovascular Disease in LMIC. DeFronzo, Nicolas Musi. To prevent one case of diabetes during a period of three years, 6. (2016) Feasibility of a brief, intensive weight loss intervention to improve reproductive outcomes in obese, subfertile women: a pilot study. Hewell, Lewis Van Brackle. The institutional review board at each center approved the protocol, and all participants gave written informed consent. (2017) How are qualitative methods used in diabetes research. Brantley, Laura P. Andrews. The intensive lifestyle intervention was at least as effective in older participants as it was in younger participants. Wang, W. Gene Interacts With Gestational Weight Gain on Postpartum Glycemic Changes: A Longitudinal Study in Women With Prior Gestational Diabetes Mellitus. (2016) Prenatal care in a specialized diabetes in pregnancy program improves compliance with postpartum testing in GDM women. Journal of Traditional and Complementary Medicine 6:4, 332-336. Rock. None of these results were materially affected by adjustment for base-line characteristics. Delahanty, M. D. (2016) Behavioral Treatment of the Patient with Obesity. Knapp, Leonard E. Abstract Background Type 2 diabetes affects approximately 8 percent of adults in the United States. (2016) Effect of dose of behavioral treatment for obesity on binge eating severity. CrossRef 341 Pan Xi, Rui Hai Liu. Sherwood, Cheryl L. (2016) Metabolic Markers to Predict Incident Diabetes Mellitus in Statin-Treated Patients (from the Treating to New Targets and the Stroke Prevention by Aggressive Reduction in Cholesterol Levels Trials). Meeks, Karien Stronks, Adebowale Adeyemo, Juliet Addo, Silver Bahendeka, Erik Beune, Ellis Owusu-Dabo, Ina Danquah, Cecilia Galbete, Peter Henneman, Kerstin Klipstein-Grobusch, Frank P. Hagamen, C. W. Chew, R. (2016) Strategies and Challenges in Clinical Trials Targeting Human Aging. Predictors of progression from impaired glucose tolerance to NIDDM: an analysis of six prospective studies. Farrell. CrossRef 338 Chikako Oyabu, Yoshitaka Hashimoto, Takuya Fukuda, Muhei Tanaka, Mai Asano, Masahiro Yamazaki, Michiaki Fukui. (2016) Screening for Dysglycemia: Connecting Supply and Demand to Slow Growth in Diabetes Incidence. Glass. (2016) The Diabetes Remission Clinical Trial (DiRECT): protocol for a cluster randomised trial. Leos, J. Deane. Lange, E. Hill, J. CrossRef 253 Amin Hasanvand, Hossein Amini-khoei, Mohammad-Reza Hadian, Alireza Abdollahi, Seyed Mohammad Tavangar, Ahmad Reza Dehpour, Elika Semiei, Shahram Ejtemaei Mehr. CrossRef 290 Masoumeh Namadian, Justin Presseau, Margaret C. Madero, Mike Payne, Laura Happe, Roger Matanich, Andrew Renda, Todd Prewitt. Endocrinology and Metabolism Clinics of North America 45:4, 751-764. Ford, Mark Gorman, Walter N. 11 The incidence of diabetes differed significantly among the three groups (P ). CrossRef 170 Jacob Hartz, Leah Yingling, Tiffany M. Endocrinology and Metabolism Clinics of North America 45:3, 553-564. CrossRef 365 S. A.
![]()
The analysis included all participants, whether or not diabetes had been diagnosed. 17 Statistical Analysis and Early Closure Random treatment assignments were stratified according to the clinical center. Adobe Flash Player is required to view this feature. HEAL and Physical Activity. A. This is a chemical in the brain that helps promote wakefulness. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. (Home and Garden Bulletin no. V. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance: the Da Qing IGT and Diabetes Study. Sosenko, John P. (2016) Prevalence and risk of diabetes based on family history in the Shanghai High-Risk Diabetic Screen (SHiDS) study. CrossRef 68 Stephanie Studenski, Luigi Ferrucci. The goals for the participants assigned to the intensive lifestyle intervention were to achieve and maintain a weight reduction of at least 7 percent of initial body weight through a healthy low-calorie, low-fat diet and to engage in physical activity of moderate intensity, such as brisk walking, for at least 150 minutes per week. Adherence to the treatment regimen was assessed quarterly on the basis of pill counts and structured interviews. Adobe Flash Player is required to view this feature. (2017) Physical Activity in Obese Type 2 Diabetes After Gastric Bypass or Medical Management. (2016) What Does Evidence-Based Mean for Nutrition Educators. Type 2 Diabetes in the Middle East and North Africa (MENA). Walker, J. Sharma, S. Adobe Flash Player is required to view this feature. Villareal. Adobe Flash Player is required to view this feature. CrossRef 105 Yoshihito Fujita, Nobuya Inagaki. CrossRef 33 Xiuying Zhang, Zhiwei Fang, Chunfang Zhang, Huihua Xia, Zhuye Jie, Xueyao Han, Yingli Chen, Linong Ji. (2016) Direct comparisons of commercial weight-loss programs on weight, waist circumference, and blood pressure: a systematic review. (2016) Nutrition for the Prevention of Chronic Diseases. (2016) Cinnamon extract lowers glucose, insulin and cholesterol in people with elevated serum glucose. (2016) Obesity and Life Expectancy with and without Diabetes in Adults Aged 55 Years and Older in the Netherlands: A Prospective Cohort Study. Herman. Endocrinology and Metabolism Clinics of North America 45:3, 565-580. Hane. Leach, C. The lifestyle intervention was particularly effective, with one case of diabetes prevented per seven persons treated for three years. Guest. Polczynski, M. (2016) Graphene nanoflakes on transparent glass electrode sensor for electrochemical sensing of anti-diabetic drug. Millen. 4 Since current methods of treating diabetes remain inadequate, prevention is preferable. Larsen, A. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. 9 would have to receive metformin. (2016) The impact of changing economic conditions on overweight risk among children in California from 2008 to 2012. Kaye Kramer, Rachel G. L. Bray, MD: Progress in Obesity—Multidisciplinary Research, Multidimensional Man. A. N. Discussion Our results support the hypothesis that type 2 diabetes can be prevented or delayed in persons at high risk for the disease. (2016) Body habitus in heart failure: understanding the mechanisms and clinical significance of the obesity paradox. Chan. Parker, Holly Wyatt, Cheryl L. Be a part of the WebMD Answers family and share your knowledge and experiences with others. (2016) International Models of Care that Address the Growing Diabetes Prevalence in Developing Countries. Pompi, E. Bertoni. Adobe Flash Player is required to view this feature. CrossRef 262 Fahim Abbasi, Payal Kohli, Gerald M. Wadden. Botti, M. Jang. Morbidity and Mortality Weekly Report 65:43, 1202. Endocrinology and Metabolism Clinics of North America 45:4, 905-921. H. (2017) A machine learning-based framework to identify type 2 diabetes through electronic health records. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Dasari, Reena Oza-Frank, K. The important thing is that all these private insurance plans typically have some sort of deductible and some sort of co-pay. Usual daily caloric intake during the previous year, including calories from fat, carbohydrate, protein, and other nutrients, was assessed at base line and at one year with the use of a modified version of the Block food-frequency questionnaire. Austad, Nir Barzilai, James L. 2016. Scott, Raymond C. Kriska. Roumain, D. (2017) A lifestyle intervention in primary care prevents deterioration of insulin resistance in patients with impaired glucose tolerance: A randomised controlled trial. M. (2017) Diabetic Neuropathy: A Position Statement by the American Diabetes Association. The blinded treatment phase was terminated one year early, in May 2001, on the advice of the data monitoring board, on the basis of data obtained through March 31, 2001, the closing date for this report. The study design and analysis followed the intention-to-treat principle. Wolfe, B. CrossRef 124 Gang Luo. M. Person, Stephenie C. Bowersox. (2016) Randomized Controlled Study of Metformin and Sitagliptin on Long-term Normoglycemia Remission in African American Patients With Hyperglycemic Crises. Delp, Wayne W Campbell, Carol J Boushey, Tamara S Hannon, Nana Gletsu-Miller. (2017) Gene expression signature: a powerful approach for drug discovery in diabetes. Adobe Flash Player is required to view this feature. L. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Adobe Flash Player is required to view this feature. Bond, Falko F. CrossRef 24 Muyesser Sayki Arslan, Esra Tutal, Mustafa Sahin, Melia Karakose, Bekir Ucan, Gulfer Ozturk, Erman Cakal, Zeynep Biyikli Gencturk, Mustafa Ozbek, Tuncay Delibasi. Rana, John D. (2016) Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease. Mikami, P. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Fang, X. CrossRef 371 Sharon Watts, Jino Y. Poirier, E. Molitch, T. Kushner. CrossRef 53 Willy Marcos Valencia, Hermes Florez. Fixed-effects models with the assumption of normally distributed errors 20 were used to assess differences over time in body weight and plasma glucose and glycosylated hemoglobin values among the three groups. Kocal, S. CrossRef 29 Karlijn A. Johannes, P. Ramachandran. Finer. ) 15 Step by step: eating to lower your high blood cholesterol. (2017) Comparing methods of targeting obesity interventions in populations: An agent-based simulation. (2016) Management of obesity in patients with type 2 diabetes mellitus in primary care. (2016) Assessment and management of severely obese children and adolescents. 0, 7. DeJoy, Robert J. Frankovich. CrossRef 85 W S Leslie, R Taylor, L Harris, M E J Lean. Lipscombe. CrossRef 76 Rodica Pop-Busui, Andrew J. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. We hypothesized that modifying these factors with a lifestyle-intervention program or the administration of metformin would prevent or delay the development of diabetes. (2016) Development and evaluation of an enhanced diabetes prevention program with psychosocial support for urban American Indians and Alaska natives: A randomized controlled trial. (2016) Maternal diet quality and nutrient intake in the gestational period: results from the delta healthy sprouts comparative impact trial. Murabito, R. Perri. (2017) Germinated Thai Black Rice Extract Protects Experimental Diabetic Rats from Oxidative Stress and Other Diabetes-Related Consequences. Griswold, Mohammed K. Sangster, J. Kula, M. Rosella. Kong, Juliana C. Interventions for preventing gestational diabetes mellitus: an overview of Cochrane Reviews. Wells, Renata J. Shaw, R. 14 The Food Guide Pyramid. (2017) Menopause, hormone therapy and diabetes. Ma, Peter C. 2017. Recruitment was designed to enroll approximately half the participants from racial or ethnic minority groups. Swigert. Diabetes mellitus: subclinical cardiovascular disease and risk of incident cardiovascular disease and all-cause mortality. (2016) Geographical variation in the progression of type 2 diabetes in Peru: The CRONICAS Cohort Study. (2017) Circulating cytokines as determinants of weight loss-induced improvements in insulin sensitivity. (2017) Evaluating surrogate marker information using censored data. Phillips. Simonson, Ann Goebel-Fabbri, Kathleen Foster, Florencia Halperin, Ashley Vernon, Allison B. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U. Journal of Diabetes and its Complications 30:5, 935-943. Donnelly, Yixi Bi, E. CrossRef 350 Saeed Mehrang, Elina Helander, Angela Chieh, Ilkka Korhonen. Obesity Management for the Treatment of Type 2 Diabetes. Schwartz, Walter N. Nutrition Therapy for the Prevention and Treatment of Prediabetes and Diabetes. CrossRef 180 Michael E. Ali, Nicholas J Wareham. (2017) Prevention of type 2 diabetes mellitus by changes in diet among subjects with abnormal glucose metabolism: a randomized clinical trial. CrossRef 354 Jose C. Schulze, Joachim Spranger, Liam Smeeth, Charles Agyemang. Kashyap. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Optimal Nutrition for the Older Adults. The study had inadequate power to assess the significance of effects within the subgroups, nor were such tests planned. (2016) Interventions that cause weight loss and the impact on cardiovascular risk factors: a systematic review and meta-analysis. A. A. (2016) Catechol-O-methyltransferase association with hemoglobin A1c. For example, data on weight were available for 3085 persons at 0. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Lyman, D. Thomson, Denise Roe, Maria Altbach, Jean-Philippe Galons, Alison Stopeck, Patricia A. Jackson Foundation for support services provided under subcontract with the Coordinating Center. (2016) Detecting Dysglycemia Using the 2015 United States Preventive Services Task Force Screening Criteria: A Cohort Analysis of Community Health Center Patients. Full Text 40 Ellen E. CrossRef 59 Sam Dagogo-Jack. Welsh, R. Staiano, Myra Altman, Jeanne Lindros, Angela Lima, Sandra G. The 1997 American Diabetes Association and 1999 World Health Organization criteria for hyperglycemia in the diagnosis and prediction of diabetes mellitus. CrossRef 244 E. CrossRef 101 Xuanping Zhang, Giuseppina Imperatore, William Thomas, Yiling J. Howard. (2016) Zinc-Associated Variant in. (2016) Awareness of Pre-diabetes or Diabetes and Associated Factors in People With Psychosis. CrossRef 324 Cynthia J Herrick, Byron W Yount, Amy A Eyler. Ford, Jennifer Sjaarda, Kripa Raman, Matthew McQueen, ShunFu Lee, Heinz Haenel, Gregory R. CrossRef 74 Kai Jin, Lis Neubeck, Janice Gullick, Fung Koo, Ding Ding. CrossRef 77 Bethany Warren, James S Pankow, Kunihiro Matsushita, Naresh M Punjabi, Natalie R Daya, Morgan Grams, Mark Woodward, Elizabeth Selvin. Adobe Flash Player is required to view this feature. Stevenson, V. There are various formulations and doses that can be changed to meet your needs. CrossRef 177 Neil Wright, Jerry Wales. James, N. (2016) Dose-Response Relationship between Dietary Magnesium Intake and Risk of Type 2 Diabetes Mellitus: A Systematic Review and Meta-Regression Analysis of Prospective Cohort Studies. Rodgers. e1. CrossRef 232 Ali Abbasi, Anna-Stina Sahlqvist, Luca Lotta, Julia M. Steinle, Charles Billington, Maria Hughes, Fatima Makki, Robert G. CrossRef 145 Yasmine Ali Abdelhamid, Palash Kar, Mark E. Preiss, N. CrossRef 114 Jagriti Narang, Nitesh Malhotra, Chaitali Singhal, Rishabh Bhatia, Vikas Kathuria, Manan Jain. (2016) Dynamics in insulin requirements and treatment safety. CrossRef 207 Anand Vaidya, Liufu Cui, Lixia Sun, Bing Lu, Shuohua Chen, Xing Liu, Yong Zhou, Xiurong Liu, Xiaobing Xie, Frank B. CrossRef 278 Jason Kam, Swati Puranik, Rama Yadav, Hanna R. (2016) Walking as a social practice: dispersed walking and the organisation of everyday practices. Katz, C. D. Eligible persons were excluded if they were taking medicines known to alter glucose tolerance or if they had illnesses that could seriously reduce their life expectancy or their ability to participate in the trial. Bashan, R. Results The average follow-up was 2. (2017) Non-pharmacological interventions in non-alcoholic fatty liver disease patients. Roy, S. Nilsson, Louise Bennet. Get health information delivered straight to your inbox. Mukamal, Daniel I. (2016) Methodological quality of behavioural weight loss studies: a systematic review. Powell-Wiley. Johnson, D. S. Schweizer, E. (2016) Automatically explaining machine learning prediction results: a demonstration on type 2 diabetes risk prediction. Franco, Nicholas J Wareham. The effect of metformin was less with a lower body-mass index or a lower fasting glucose concentration than with higher values for those variables. Hispanic Adults: A Systematic Review of Culturally Tailored Interventions. Hemachandra Reddy. 2016. 8 cases per 100 person-years in the placebo, metformin, and lifestyle groups, respectively. J. Lean. Jia. Rock. Wang, and J. Implementation of group sequential logrank tests in a maximum duration trial. Lichtenstein. HEAL for Diabetes. Hu. Bao, C. Patel. Gudzune. (2016) Prevention and Care Programs Addressing the Growing Prevalence of Diabetes in China. CrossRef 178 David Preiss, Adem Dawed, Paul Welsh, Alison Heggie, Angus G. Mahady, Jacob George. (2016) Prospective evaluation of abnormal glucose metabolism and insulin resistance in patients with atypical endometrial hyperplasia and endometrial cancer. CrossRef 80 Marion J. CrossRef 25 Hsiao-Feng Hu, Hsin Hsiu, Ciao-Jyuan Sung, Chien-Hsing Lee. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Venkat Narayan. L. CrossRef 246 Eugene Han, Myoung Soo Kim, Yu Seun Kim, Eun Seok Kang. CrossRef 315 Antonino Di Pino, Walter Currenti, Francesca Urbano, Concetta Mantegna, Giacomo Purrazzo, Salvatore Piro, Francesco Purrello, Agata Maria Rabuazzo. Hellgren, Per-Anders Jansson, Hans Wedel, Ulf Lindblad. (2016) Cardiometabolic Risk Factor Changes Observed in Diabetes Prevention Programs in US Settings: A Systematic Review and Meta-analysis. Some risk factors — elevated plasma glucose concentrations in the fasting state and after an oral glucose load, overweight, and a sedentary lifestyle — are potentially reversible. (2016) The relationship of fasting hyperglycemia to changes in fat and muscle mass after exercise training in type 2 diabetes. (2016) Changes in Overall Diet Quality and Subsequent Type 2 Diabetes Risk: Three U. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. P. CrossRef 50 Okon Essien, Akaninyene Otu, Victor Umoh, Ofem Enang, Joseph Paul Hicks, John Walley, Stephen L Atkin. Gregg. Ali, K. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Results Study Cohort and Follow-up From 1996 to 1999, we randomly assigned 3234 study participants to one of the three interventions (1082 to placebo, 1073 to metformin, and 1079 to the intensive lifestyle intervention). Treatment with metformin was initiated at a dose of 850 mg taken orally once a day, with placebo tablets also given once a day initially. Neither interaction was explained by the other variable or by age. (2017) Lessons from Launching the Diabetes Prevention Program in a Large Integrated Health Care Delivery System: A Case Study. Venn. Altman, Rodney A. Prediction of Prediabetes and Its Prevention by Functional Food Compounds. Adobe Flash Player is required to view this feature. (2016) Risk and treatment effect heterogeneity: re-analysis of individual participant data from 32 large clinical trials. 7 percent, and 14. (2016) USE OF METFORMIN IN CLINICAL ENDOCRINOLOGY. Schafer, Vincent C. The advantage of the lifestyle intervention over metformin was greater in older persons and those with a lower body-mass index than in younger persons and those with a higher body-mass index. CrossRef 22 Jay Desai, Gretchen Taylor, Gabriela Vazquez-Benitez, Sara Vine, Julie Anderson, Joyce E. Adobe Flash Player is required to view this feature. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. (2016) Phase II study of metformin for reduction of obesity-associated breast cancer risk: a randomized controlled trial protocol. L. Adobe Flash Player is required to view this feature. Vijaya, S. Digenio. 21 Edelstein SL, Knowler WC, Bain RP, et al. Gurusamy, R. Stuenkel. CrossRef 104 N. Adobe Flash Player is required to view this feature. 1, and 5. Lean, Lisa Te Morenga. Metformin and the lifestyle intervention were similarly effective in restoring normal fasting glucose values, but the lifestyle intervention was more effective in restoring normal post-load glucose values. Previous studies have not demonstrated that drugs used to treat diabetes are effective for its prevention, perhaps because of small samples and the lack of data on adherence to the prescribed regimens. Arun, A. C. S. CrossRef 224 Matti Uusitupa. Mantzoros. CrossRef 241 Catherine Kim, Elizabeth Barrett-Connor, Vanita R. Kernan. (2017) Transcriptomic effects of metformin in skeletal muscle arteries of obese insulin-resistant rats. (2016) Model Programs to Address Obesity and Cardiometabolic Disease: Interventions for Suboptimal Nutrition and Sedentary Lifestyles. As long as the fasting plasma glucose concentration was less than 140 mg per deciliter, participants were asked to monitor their blood glucose and to continue their assigned study treatment. Marinik, Richard A. Mehta, A. (2016) Pilot Feasibility Study of an Educational Intervention in Women With Gestational Diabetes. CrossRef 6 Vera K Tsenkova. S. Trimmer, T. Mazul, Heather Highland, K. H. Garg. (2017) Later chronotype is associated with higher hemoglobin A1c in prediabetes patients. Kriska. Hackett, Andrew Steptoe. Peek. Journal of Epidemiology and Community Health 70:9, 874-880. CrossRef 249 Mary Beth Weber, Harish Ranjani, Lisa R. CrossRef 60 Yasmin Khan, Osama Hamdy. Journal of Stroke and Cerebrovascular Diseases 25:7, 1705-1712. Uthman, Louise Hartley, Karen Rees, Fiona Taylor, Shah Ebrahim, Aileen Clarke. (2016) Nutrition in Clinical Medicine: A Core Competency for Healthcare Providers. (2016) Sleep disturbances compared to traditional risk factors for diabetes development: Systematic review and meta-analysis. Journal of Occupational and Environmental Medicine 58:11, 1113-1120. Tong. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. Adobe Flash Player is required to view this feature. Lee, A. On the basis of these rates, the estimated number of persons who would need to be treated for three years to prevent one case of diabetes during this period is 6. F. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Adobe Flash Player is required to view this feature. Douglas Case, David C. (2016) Sugar and Type 2 diabetes. (2017) A parallel curriculum in lifestyle medicine. The Diabetes Prevention Program: design and methods for a clinical trial in the prevention of type 2 diabetes. J. Epidemiology of Type 2 Diabetes. Harris, P. Early detection of undiagnosed diabetes mellitus: a US perspective. (2016) Interprofessional Collaborative Practice Models in Chronic Disease Management. Hsu, A. (2016) Advice to walk after meals is more effective for lowering postprandial glycaemia in type 2 diabetes mellitus than advice that does not specify timing: a randomised crossover study. Adobe Flash Player is required to view this feature. Zomer, K. (2016) Metformin. Sainsbury. Kulkarni. Lifestyle Interventions for the Prevention of Type 2 Diabetes in Obese Children and Youth. M. CrossRef 90 Nancy Tarr Anderson, Ellen P. (2016) Implications of supermarket access, neighbourhood walkability and poverty rates for diabetes risk in an employee population. Best Practices for Choosing Nutrition Education Interventions Based on the Strength of the Evidence. Holleman, Pia Roman, Zongshan Lai, Nicholas W. Gray, Melanie J. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Adobe Flash Player is required to view this feature. Pal, K. The results of our study extend previous data showing that lifestyle interventions can reduce the incidence of diabetes 7,8 and demonstrate the applicability of this finding to the ethnically and culturally diverse population of the United States. Greenway. (2016) Bariatric Surgery. Tapp, J. (2017) Society for Health Psychology (APA Division 38) and Society of Behavioral Medicine joint position statement on the Medicare Diabetes Prevention Program. There was a similar temporal pattern in the values for glycosylated hemoglobin, except that the values in the metformin group were in between those in the lifestyle-intervention and placebo groups. Mann, Joseph Palmisano, Jenny J. If diabetes was diagnosed, the participants and their physicians were informed and glucose-tolerance tests were discontinued, but fasting plasma glucose was measured every six months, with glycosylated hemoglobin measured annually. 2017. Venkat Narayan, Lawrence S. CrossRef 171 Tiange Wang, Huikun Liu, Leishen Wang, Tao Huang, Weiqin Li, Yan Zheng, Yoriko Heianza, Dianjianyi Sun, Junhong Leng, Shuang Zhang, Nan Li, Gang Hu, Lu Qi. Albert, Dennis T. (2017) The Arab American experience with diabetes: Perceptions, myths and implications for culturally-specific interventions. Mathers, Carl Peters, George Thom, Alison Barnes, Sharon Kean, Yvonne McIlvenna, Angela Rodrigues, Lucia Rehackova, Sviatlana Zhyzhneuskaya, Roy Taylor, Mike E. Graff, A. L. Thus, it should also be possible to delay or prevent the development of complications, substantially reducing the individual and public health burden of diabetes. Journal of Diabetes and its Complications 31:1, 288-290. Bakker, Eva Corpeleijn, Gerjan Navis. K. Learn more about these popular experts selected by the WebMD Editorial Staff. Anjana, Mohammed K. Jenkins, M. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. (2017) Weight losses with low-energy formula diets in obese patients with and without type 2 diabetes: systematic review and meta-analysis. 16 Kriska AM, Caspersen CJ. CrossRef 394 Shuji Inada, Kazuhiro Yoshiuchi, Yoko Iizuka, Ken Ohashi, Hiroe Kikuchi, Yoshiharu Yamamoto, Takashi Kadowaki, Akira Akabayashi. (2016) Anti-inflammatory effect of AMPK signaling pathway in rat model of diabetic neuropathy. Andersson, J. (2017) Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus. Janson. (2017) Beneficial effects of replacing diet beverages with water on type 2 diabetic obese women following a hypo-energetic diet: A randomized, 24-week clinical trial. Southerland, Jennifer Webster-Cyriaque, Helene Bednarsh, Charles P. Violino, E. Deane, Peter G. Most people who have narcolepsy have low levels of hypocretin. (2016) Severe hypoglycemia in the Look AHEAD Trial. (2017) Combining laser-Doppler flowmetry measurements with spectral analysis to study different microcirculatory effects in human prediabetic and diabetic subjects. If the fasting plasma glucose concentration reached or exceeded 140 mg per deciliter, the study medication was discontinued and the participant was referred to his or her physician for treatment. CrossRef 98 Vlad Ratziu. Sniehotta. 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2475-2478. 8, and 4. 5 In contrast, metformin was effective in our study, although less so than the lifestyle intervention. (2016) Effects of exercise training alone vs a combined exercise and nutritional lifestyle intervention on glucose homeostasis in prediabetic individu
